Magnesium and melatonin are two popular supplements used by people who have difficulty sleeping. Although both are associated with sleep, they work differently and are not interchangeable.
Magnesium vs. Melatonin: The Quick Answer
Melatonin has stronger evidence for certain sleep-timing problems, such as jet lag. However, neither magnesium nor melatonin is recommended as a routine treatment for chronic insomnia because the available evidence is insufficient. For adults with chronic insomnia, cognitive behavioral therapy for insomnia (CBT-I) is a more strongly supported treatment. See the National Center for Complementary and Integrative Health (NCCIH) and the American Academy of Sleep Medicine guideline.
The better choice depends on the underlying problem. Someone whose sleep schedule is disrupted by traveling across time zones may benefit from appropriately timed melatonin. Someone with a magnesium deficiency should have that deficiency addressed, but taking additional magnesium does not guarantee better sleep.





